Mechanical Vacuum Erection Devices

Vacuum Erection Devices Details:

• Used in male erectile dysfunction.
• Consist of a rigid cylinder which is placed over the penis.
• The air is sucked out of the cylinder by a hand pump or electrical pump.
• The resulting negative pressure around the penis increases penile corporeal blood flow.
• The produced erection is maintained by using a constriction ring around the base of the penis which reduces corporeal venous drainage.

Clinical Efficacy:

• Long-term success in ~60% of patients.[1]

References:
1 - Oakley N, Moore KT (1998). Vacuum devices in erectile dysfunction: indications and efficacy. Br J Urol 1998; 82:673-81

Tags: Corporeal Blood Flow - Male Erectile Dysfunction - Penis - Vacuum Erection Device
Posted by Medicalchemy
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Drug Induced Male Erectile Dysfunction

Drug Induced Male Erectile Dysfunction Overview:

• The physiologic mechanisms associated with the normal sexual response include vascular, neurogenic, psychogenic, & hormonal factors.
• These physiologic mechanisms are coordinated centrally in the hypothalamus, limbic system, & cerebral cortex.
• Drugs may induce erectile dysfunction by altering any of the physiological mechanisms outlined above, i.e. adrenergic inhibition, adrenergic-receptor blockade, anticholinergic action, as well as endocrine & sedative effects.

Central nervous system drugs:

• Benzodiazepines
• Butyrophenones
• Cyclobenzaprine
• Monoamine oxidase inhibitors
• Orphenadrine
• Phenothiazines
• SSRIs
• Thioxanthenes
• Tricyclic antidepressants

Antihypertensive drugs:

• Beta-blockers (esp propranolol)
• Clonidine
• Diuretics
• Guanethidine
• Methyldopa
• Thiazide diuretics

Others:

• Antiandrogens
• Antineoplastic drugs
• Cimetidine
• Clofibrate
• Digoxin
• Ethanol
• Finasteride
• Metoclopramide
• Nicotine
• Oestrogens
• Propantheline
• Sedating antihistamines

Tags: Drug-induced - Erectile Dysfunction - Impotence - Male Erectile Dysfunction
Posted by Medicalchemy
Medicalchemy Group: History of Medicine - Images - Mnemonics - Syndromes - Acute Medicine - Anaesthesiology - Anatomy - Anthropology - Biochemistry - Cardiology - Dentistry - Dermatology - Drug ADR - Drugs - Embryology - Emergency Medicine - Endocrinology - Epidemiology - Family Medicine - Forensic Medicine - Gastroenterology - Genes - Genetics - Geriatrics - Gynecology - Haematology - Health Informatics - Hepatology - Immunology - Infection - Intensive Care - Medical Dictionary - Medical Education - Medical Statistics - Metabolic Medicine - Microbiology - Nephrology - Neuroanatomy - Neuroscience - Nuclear Medicine - Nutrition - Obstetrics - Occupational Health - Oncology - Ophthalmology - Orthopaedics - Otolaryngology - Paediatrics - Palliative Care - Parasitology - Pathology - Pharmacology - Physiology - Proteomics - Psychiatry - Public Health - Radiology - Respiratory - Rehabilitation - Rheumatology - Sports Medicine - Surgery - Toxicology - Tropical Medicine - Urology - Vascular - Virology.