Drug Induced Male Erectile Dysfunction

Drug Induced Male Erectile Dysfunction Overview:

• The physiologic mechanisms associated with the normal sexual response include vascular, neurogenic, psychogenic, & hormonal factors.
• These physiologic mechanisms are coordinated centrally in the hypothalamus, limbic system, & cerebral cortex.
• Drugs may induce erectile dysfunction by altering any of the physiological mechanisms outlined above, i.e. adrenergic inhibition, adrenergic-receptor blockade, anticholinergic action, as well as endocrine & sedative effects.

Central nervous system drugs:

• Benzodiazepines
• Butyrophenones
• Cyclobenzaprine
• Monoamine oxidase inhibitors
• Orphenadrine
• Phenothiazines
• SSRIs
• Thioxanthenes
• Tricyclic antidepressants

Antihypertensive drugs:

• Beta-blockers (esp propranolol)
• Clonidine
• Diuretics
• Guanethidine
• Methyldopa
• Thiazide diuretics

Others:

• Antiandrogens
• Antineoplastic drugs
• Cimetidine
• Clofibrate
• Digoxin
• Ethanol
• Finasteride
• Metoclopramide
• Nicotine
• Oestrogens
• Propantheline
• Sedating antihistamines

Tags: Drug-induced - Erectile Dysfunction - Impotence - Male Erectile Dysfunction
Posted by Medicalchemy
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